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Sertoli cell-specific ablation of miR-17-92 cluster significantly alters whole testis transcriptome without apparent phenotypic effects

MicroRNAs are frequently organized into polycistronic clusters whose transcription is controlled by a single promoter. The miR-17-92 cluster is expressed in most embryonic and postnatal organs. It is a potent oncogene associated to several types of cancer and it is involved in several important deve...

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Detalles Bibliográficos
Autores principales: Hurtado, Alicia, Real, Francisca M., Palomino, Rogelio, Carmona, Francisco David, Burgos, Miguel, Jiménez, Rafael, Barrionuevo, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967698/
https://www.ncbi.nlm.nih.gov/pubmed/29795630
http://dx.doi.org/10.1371/journal.pone.0197685