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Thymulin, free or bound to PBCA nanoparticles, protects mice against chronic septic inflammation

In the present work, we aimed to study the effects of free and polybutylcyanoacrylate nanoparticle-bound thymulin on immune cell activity in mice with chronic inflammation. NF-κB, MAPK, and PKC-θ signaling pathway activity was assessed, alongside Hsp72, Hsp90-α, and TLR4 expression and levels of apo...

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Detalles Bibliográficos
Autores principales: Novoselova, Elena G., Lunin, Sergey M., Glushkova, Olga V., Khrenov, Maxim O., Parfenyuk, Svetlana B., Zakharova, Nadezhda M., Fesenko, Evgeny E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967805/
https://www.ncbi.nlm.nih.gov/pubmed/29795607
http://dx.doi.org/10.1371/journal.pone.0197601