Defects in nerve conduction velocity and different muscle fibre-type specificity contribute to muscle weakness in Ts1Cje Down syndrome mouse model

BACKGROUND: Down syndrome (DS) is a genetic disorder caused by presence of extra copy of human chromosome 21. It is characterised by several clinical phenotypes. Motor dysfunction due to hypotonia is commonly seen in individuals with DS and its etiology is yet unknown. Ts1Cje, which has a partial tr...

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Detalles Bibliográficos
Autores principales: Bala, Usman, Leong, Melody Pui-Yee, Lim, Chai Ling, Shahar, Hayati Kadir, Othman, Fauziah, Lai, Mei-I, Law, Zhe-Kang, Ramli, Khairunnisa, Htwe, Ohnmar, Ling, King-Hwa, Cheah, Pike-See
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967806/
https://www.ncbi.nlm.nih.gov/pubmed/29795634
http://dx.doi.org/10.1371/journal.pone.0197711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967806/
https://www.ncbi.nlm.nih.gov/pubmed/29795634
http://dx.doi.org/10.1371/journal.pone.0197711

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