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Prickle is phosphorylated by Nemo and targeted for degradation to maintain Prickle/Spiny-legs isoform balance during planar cell polarity establishment

Planar cell polarity (PCP) instructs tissue patterning in a wide range of organisms from fruit flies to humans. PCP signaling coordinates cell behavior across tissues and is integrated by cells to couple cell fate identity with position in a developing tissue. In the fly eye, PCP signaling is requir...

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Detalles Bibliográficos
Autores principales: Collu, Giovanna M., Jenny, Andreas, Gaengel, Konstantin, Mirkovic, Ivana, Chin, Mei-ling, Weber, Ursula, Smith, Michael J., Mlodzik, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967807/
https://www.ncbi.nlm.nih.gov/pubmed/29758044
http://dx.doi.org/10.1371/journal.pgen.1007391