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Association of serum high-mobility group box protein 1 level with outcomes of acute exacerbation of idiopathic pulmonary fibrosis and fibrosing nonspecific interstitial pneumonia

BACKGROUND AND OBJECTIVE: High-mobility group box 1 (HMGB1) protein is important in acute lung injury. However, the role of HMGB-1 in acute exacerbation of fibrosing interstitial pneumonia (AE-FIP) has not been adequately studied. METHODS: We prospectively measured serum HMGB1 level from disease ons...

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Detalles Bibliográficos
Autores principales: Shimizu, Hiroshige, Sakamoto, Susumu, Isshiki, Takuma, Furuya, Kenta, Kurosaki, Atsuko, Homma, Sakae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967827/
https://www.ncbi.nlm.nih.gov/pubmed/29795561
http://dx.doi.org/10.1371/journal.pone.0196558