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Human microRNAs preferentially target genes with intermediate levels of expression and its formation by mammalian evolution

MicroRNAs (miRNAs) are short, endogenous RNAs that post-transcriptionally repress mRNAs. Over the course of evolution, many new miRNAs are known to have emerged and added to the existing miRNA repertoires of drosophilids and vertebrates. Despite the large number of miRNAs in existence, the complemen...

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Detalles Bibliográficos
Autores principales: Iwama, Hisakazu, Kato, Kiyohito, Imachi, Hitomi, Murao, Koji, Masaki, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967834/
https://www.ncbi.nlm.nih.gov/pubmed/29795674
http://dx.doi.org/10.1371/journal.pone.0198142