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Human microRNAs preferentially target genes with intermediate levels of expression and its formation by mammalian evolution
MicroRNAs (miRNAs) are short, endogenous RNAs that post-transcriptionally repress mRNAs. Over the course of evolution, many new miRNAs are known to have emerged and added to the existing miRNA repertoires of drosophilids and vertebrates. Despite the large number of miRNAs in existence, the complemen...
Autores principales: | Iwama, Hisakazu, Kato, Kiyohito, Imachi, Hitomi, Murao, Koji, Masaki, Tsutomu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967834/ https://www.ncbi.nlm.nih.gov/pubmed/29795674 http://dx.doi.org/10.1371/journal.pone.0198142 |
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