Cargando…
Hepatitis transactivator protein X promotes extracellular matrix modification through HIF/LOX pathway in liver cancer
Hepatocellular carcinoma (HCC), accounting for 90% of primary liver cancer, is a lethal malignancy that is tightly associated with chronic hepatitis B virus (HBV) infection. HBV encodes a viral onco-protein, transactivator protein X (HBx), which interacts with proteins of hepatocytes to promote onco...
Autores principales: | , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968027/ https://www.ncbi.nlm.nih.gov/pubmed/29799025 http://dx.doi.org/10.1038/s41389-018-0052-8 |