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Update on glycerol-3-phosphate acyltransferases: the roles in the development of insulin resistance

Glycerol-3-phosphate acyltransferase (GPAT) is the rate-limiting enzyme in the de novo pathway of glycerolipid synthesis. It catalyzes the conversion of glycerol-3-phosphate and long-chain acyl-CoA to lysophosphatidic acid. In mammals, four isoforms of GPATs have been identified based on subcellular...

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Detalles Bibliográficos
Autores principales: Yu, Jing, Loh, Kim, Song, Zhi-yuan, Yang, He-qin, Zhang, Yi, Lin, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968029/
https://www.ncbi.nlm.nih.gov/pubmed/29799006
http://dx.doi.org/10.1038/s41387-018-0045-x