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AIRE promotes androgen-independent prostate cancer by directly regulating IL-6 and modulating tumor microenvironment
Early stage prostate cancers are dependent on androgens for their growth and survival and androgen withdrawal causes them to regress. Progressive prostate cancers eventually acquire androgen independence rendering anti-androgen therapy ineffective. However, the factors leading to this have not been...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968032/ https://www.ncbi.nlm.nih.gov/pubmed/29795364 http://dx.doi.org/10.1038/s41389-018-0053-7 |