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AIRE promotes androgen-independent prostate cancer by directly regulating IL-6 and modulating tumor microenvironment

Early stage prostate cancers are dependent on androgens for their growth and survival and androgen withdrawal causes them to regress. Progressive prostate cancers eventually acquire androgen independence rendering anti-androgen therapy ineffective. However, the factors leading to this have not been...

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Detalles Bibliográficos
Autores principales: Kalra, Rashi, Bhagyaraj, Ella, Tiwari, Drishti, Nanduri, Ravikanth, Chacko, Anuja P., Jain, Monika, Mahajan, Sahil, Khatri, Neeraj, Gupta, Pawan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968032/
https://www.ncbi.nlm.nih.gov/pubmed/29795364
http://dx.doi.org/10.1038/s41389-018-0053-7