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Multiple roles of Sonic Hedgehog in the developing human cortex are suggested by its widespread distribution

Sonic Hedgehog (Shh) plays an instrumental role in brain development, fine-tuning processes such as cell proliferation, patterning, and fate specification. Although, mutations in the SHH pathway in humans are associated with various neurodevelopmental disorders, ranging from holoprosencephaly to sch...

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Detalles Bibliográficos
Autores principales: Memi, Fani, Zecevic, Nada, Radonjić, Nevena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968052/
https://www.ncbi.nlm.nih.gov/pubmed/29492654
http://dx.doi.org/10.1007/s00429-018-1621-5