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Multiple roles of Sonic Hedgehog in the developing human cortex are suggested by its widespread distribution
Sonic Hedgehog (Shh) plays an instrumental role in brain development, fine-tuning processes such as cell proliferation, patterning, and fate specification. Although, mutations in the SHH pathway in humans are associated with various neurodevelopmental disorders, ranging from holoprosencephaly to sch...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968052/ https://www.ncbi.nlm.nih.gov/pubmed/29492654 http://dx.doi.org/10.1007/s00429-018-1621-5 |