NMR metabolomics of fibroblasts with inherited mitochondrial Complex I mutation reveals treatment-reversible lipid and amino acid metabolism alterations

INTRODUCTION: Elucidating molecular alterations due to mitochondrial Complex I (CI) mutations may help to understand CI deficiency (CID), not only in mitochondriopathies but also as it is caused by drugs or associated to many diseases. OBJECTIVES: CID metabolic expression was investigated in Leber’s...

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Detalles Bibliográficos
Autores principales: Morvan, Daniel, Demidem, Aicha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968059/
https://www.ncbi.nlm.nih.gov/pubmed/29937703
http://dx.doi.org/10.1007/s11306-018-1345-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968059/
https://www.ncbi.nlm.nih.gov/pubmed/29937703
http://dx.doi.org/10.1007/s11306-018-1345-9

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