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A Computational Workflow for Probabilistic Quantitative in Vitro to in Vivo Extrapolation
A computational workflow was developed to facilitate the process of quantitative in vitro to in vivo extrapolation (QIVIVE), specifically the translation of in vitro concentration-response to in vivo dose-response relationships and subsequent derivation of a benchmark dose value (BMD). The workflow...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968095/ https://www.ncbi.nlm.nih.gov/pubmed/29867507 http://dx.doi.org/10.3389/fphar.2018.00508 |