Streptozotocin Impairs Proliferation and Differentiation of Adult Hippocampal Neural Stem Cells in Vitro-Correlation With Alterations in the Expression of Proteins Associated With the Insulin System

Rats intracerebroventricularily (icv) treated with streptozotocin (STZ), shown to generate an insulin resistant brain state, were used as an animal model for the sporadic form of Alzheimer’s disease (sAD). Previously, we showed in an in vivo study that 3 months after STZ icv treatment hippocampal ad...

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Detalles Bibliográficos
Autores principales: Sun, Ping, Ortega, Gabriela, Tan, Yan, Hua, Qian, Riederer, Peter F., Deckert, Jürgen, Schmitt-Böhrer, Angelika G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968103/
https://www.ncbi.nlm.nih.gov/pubmed/29867451
http://dx.doi.org/10.3389/fnagi.2018.00145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968103/
https://www.ncbi.nlm.nih.gov/pubmed/29867451
http://dx.doi.org/10.3389/fnagi.2018.00145

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