Cargando…

Ursolic Acid Ameliorates Inflammation in Cerebral Ischemia and Reperfusion Injury Possibly via High Mobility Group Box 1/Toll-Like Receptor 4/NFκB Pathway

Toll-like receptors (TLRs) play key roles in cerebral ischemia and reperfusion injury by inducing the production of inflammatory mediators, such as interleukins (ILs) and tumor necrosis factor-alpha (TNF-α). According to recent studies, ursolic acid (UA) regulates TLR signaling and exhibits notable...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yanzhe, Li, Lei, Deng, Shumin, Liu, Fang, He, Zhiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968106/
https://www.ncbi.nlm.nih.gov/pubmed/29867706
http://dx.doi.org/10.3389/fneur.2018.00253