Paeonol Ameliorates Diabetic Renal Fibrosis Through Promoting the Activation of the Nrf2/ARE Pathway via Up-Regulating Sirt1

Diabetic nephropathy (DN) is rapidly becoming the leading cause of end-stage renal disease worldwide and a major cause of morbidity and mortality in patients of diabetes. The main pathological change of DN is renal fibrosis. Paeonol (PA), a single phenolic compound extracted from the root bark of Co...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Chen, Zhiquan, Gong, Wenyan, Zou, Yezi, Xu, Futian, Chen, Lihao, Huang, Heqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968333/
https://www.ncbi.nlm.nih.gov/pubmed/29867511
http://dx.doi.org/10.3389/fphar.2018.00512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968333/
https://www.ncbi.nlm.nih.gov/pubmed/29867511
http://dx.doi.org/10.3389/fphar.2018.00512

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