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Paeonol Ameliorates Diabetic Renal Fibrosis Through Promoting the Activation of the Nrf2/ARE Pathway via Up-Regulating Sirt1
Diabetic nephropathy (DN) is rapidly becoming the leading cause of end-stage renal disease worldwide and a major cause of morbidity and mortality in patients of diabetes. The main pathological change of DN is renal fibrosis. Paeonol (PA), a single phenolic compound extracted from the root bark of Co...
Autores principales: | Zhang, Lei, Chen, Zhiquan, Gong, Wenyan, Zou, Yezi, Xu, Futian, Chen, Lihao, Huang, Heqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968333/ https://www.ncbi.nlm.nih.gov/pubmed/29867511 http://dx.doi.org/10.3389/fphar.2018.00512 |
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