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Efficacy and safety of primaquine and methylene blue for prevention of Plasmodium falciparum transmission in Mali: a phase 2, single-blind, randomised controlled trial

BACKGROUND: Primaquine and methylene blue are gametocytocidal compounds that could prevent Plasmodium falciparum transmission to mosquitoes. We aimed to assess the efficacy and safety of primaquine and methylene blue in preventing human to mosquito transmission of P falciparum among glucose-6-phosph...

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Detalles Bibliográficos
Autores principales: Dicko, Alassane, Roh, Michelle E, Diawara, Halimatou, Mahamar, Almahamoudou, Soumare, Harouna M, Lanke, Kjerstin, Bradley, John, Sanogo, Koualy, Kone, Daouda T, Diarra, Kalifa, Keita, Sekouba, Issiaka, Djibrilla, Traore, Sekou F, McCulloch, Charles, Stone, Will J R, Hwang, Jimee, Müller, Olaf, Brown, Joelle M, Srinivasan, Vinay, Drakeley, Chris, Gosling, Roly, Chen, Ingrid, Bousema, Teun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science ;, The Lancet Pub. Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968371/
https://www.ncbi.nlm.nih.gov/pubmed/29422384
http://dx.doi.org/10.1016/S1473-3099(18)30044-6