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Direct Profiling the Post-Translational Modification Codes of a Single Protein Immobilized on a Surface Using Cu-free Click Chemistry

[Image: see text] Combinatorial post-translational modifications (PTMs), which can serve as dynamic “molecular barcodes”, have been proposed to regulate distinct protein functions. However, studies of combinatorial PTMs on single protein molecules have been hindered by a lack of suitable analytical...

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Detalles Bibliográficos
Autores principales: Kim, Kyung Lock, Park, Kyeng Min, Murray, James, Kim, Kimoon, Ryu, Sung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968440/
https://www.ncbi.nlm.nih.gov/pubmed/29806008
http://dx.doi.org/10.1021/acscentsci.8b00114