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Direct Profiling the Post-Translational Modification Codes of a Single Protein Immobilized on a Surface Using Cu-free Click Chemistry
[Image: see text] Combinatorial post-translational modifications (PTMs), which can serve as dynamic “molecular barcodes”, have been proposed to regulate distinct protein functions. However, studies of combinatorial PTMs on single protein molecules have been hindered by a lack of suitable analytical...
Autores principales: | Kim, Kyung Lock, Park, Kyeng Min, Murray, James, Kim, Kimoon, Ryu, Sung Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968440/ https://www.ncbi.nlm.nih.gov/pubmed/29806008 http://dx.doi.org/10.1021/acscentsci.8b00114 |
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