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Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice

BACKGROUND: Polycystic ovary syndrome (PCOS) is a complex genetic disease with multifarious phenotypes. Many researches use dehydroepiandrosterone (DHEA) to induce PCOS in pubertal mouse models. The aim of this study was to investigate the role of GPR1 in dehydroepiandrosterone (DHEA)-induced hypera...

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Detalles Bibliográficos
Autores principales: Yang, Ya-Li, Sun, Li-Feng, Yu, Yan, Xiao, Tian-Xia, Wang, Bao-Bei, Ren, Pei-Gen, Tang, Hui-Ru, Zhang, Jian V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968470/
https://www.ncbi.nlm.nih.gov/pubmed/29793502
http://dx.doi.org/10.1186/s12958-018-0363-9