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Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice
BACKGROUND: Polycystic ovary syndrome (PCOS) is a complex genetic disease with multifarious phenotypes. Many researches use dehydroepiandrosterone (DHEA) to induce PCOS in pubertal mouse models. The aim of this study was to investigate the role of GPR1 in dehydroepiandrosterone (DHEA)-induced hypera...
Autores principales: | Yang, Ya-Li, Sun, Li-Feng, Yu, Yan, Xiao, Tian-Xia, Wang, Bao-Bei, Ren, Pei-Gen, Tang, Hui-Ru, Zhang, Jian V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968470/ https://www.ncbi.nlm.nih.gov/pubmed/29793502 http://dx.doi.org/10.1186/s12958-018-0363-9 |
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