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Abnormalities of hair structure and skin histology derived from CRISPR/Cas9-based knockout of phospholipase C-delta 1 in mice

BACKGROUND: Hairless mice have been widely applied in skin-related researches, while hairless pigs will be an ideal model for skin-related study and other biomedical researches because of the similarity of skin structure with humans. The previous study revealed that hairlessness phenotype in nude mi...

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Detalles Bibliográficos
Autores principales: Liu, Yu-Min, Liu, Wei, Jia, Jun-Shuang, Chen, Bang-Zhu, Chen, Heng-Wei, Liu, Yu, Bie, Ya-Nan, Gu, Peng, Sun, Yan, Xiao, Dong, Gu, Wei-Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968471/
https://www.ncbi.nlm.nih.gov/pubmed/29793503
http://dx.doi.org/10.1186/s12967-018-1512-9