Multivalent Antigen Presentation Enhances the Immunogenicity of a Synthetic Three-Component HIV-1 V3 Glycopeptide Vaccine

[Image: see text] HIV-1 envelope glycoproteins gp120 and gp41 are presented on the virus surface as a trimer of heterodimer and are the targets of broadly neutralizing antibodies (bNAbs). We describe here the synthesis and preliminary immunological evaluation of a three-component trivalent HIV-1 V3...

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Detalles Bibliográficos
Autores principales: Cai, Hui, Zhang, Roushu, Orwenyo, Jared, Giddens, John, Yang, Qiang, LaBranche, Celia C., Montefiori, David C., Wang, Lai-Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968512/
https://www.ncbi.nlm.nih.gov/pubmed/29806004
http://dx.doi.org/10.1021/acscentsci.8b00060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968512/
https://www.ncbi.nlm.nih.gov/pubmed/29806004
http://dx.doi.org/10.1021/acscentsci.8b00060

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