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Generation of artificial sequence-specific nucleases via a preassembled inert-template

Sequence specific nucleases are important tools for processing nucleic acids in a predictable way. Herein, we demonstrate a conceptually new approach for generating sequence-specific nucleases via a preassembled inert-template (PAIT). A fairly stable DNase I/inert-DNA complex was prepared with a cus...

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Detalles Bibliográficos
Autores principales: Xiao, Xianjin, Wu, Tongbo, Gu, Feidan, Zhao, Meiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968549/
https://www.ncbi.nlm.nih.gov/pubmed/29899930
http://dx.doi.org/10.1039/c5sc04398k