Aquaporin-4 deletion ameliorates hypoglycemia-induced BBB permeability by inhibiting inflammatory responses

BACKGROUND: Severe hypoglycemia induces brain edema by upregulating aquaporin-4 (AQP4) expression and by degrading tight junctions. Acute severe hypoglycemia induces a proinflammatory environment that may contribute to a disruption in the epithelial barrier by decreasing tight junction protein expre...

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Detalles Bibliográficos
Autores principales: Zhao, Fei, Deng, Jiangshan, Xu, Xiaofeng, Cao, Fengya, Lu, Kaili, Li, Dawei, Cheng, Xiaojuan, Wang, Xiuzhe, Zhao, Yuwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968550/
https://www.ncbi.nlm.nih.gov/pubmed/29793504
http://dx.doi.org/10.1186/s12974-018-1203-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968550/
https://www.ncbi.nlm.nih.gov/pubmed/29793504
http://dx.doi.org/10.1186/s12974-018-1203-8

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