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Long noncoding RNA AFAP1-AS1 predicts a poor prognosis and regulates non–small cell lung cancer cell proliferation by epigenetically repressing p21 expression

BACKGROUND: Mounting evidence indicates that long noncoding RNAs (lncRNAs) could play a pivotal role in cancer biology. However, the role and molecular mechanism and global genes that were mediated by lncRNA AFAP1-AS1 in non–small cell lung cancer (NSCLC) remain largely unknown. METHODS: Expression...

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Detalles Bibliográficos
Autores principales: Yin, Dandan, Lu, Xiyi, Su, Jun, He, Xuezhi, De, Wei, Yang, Jinsong, Li, Wei, Han, Liang, Zhang, Erbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968553/
https://www.ncbi.nlm.nih.gov/pubmed/29793547
http://dx.doi.org/10.1186/s12943-018-0836-7