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Long noncoding RNA AFAP1-AS1 predicts a poor prognosis and regulates non–small cell lung cancer cell proliferation by epigenetically repressing p21 expression
BACKGROUND: Mounting evidence indicates that long noncoding RNAs (lncRNAs) could play a pivotal role in cancer biology. However, the role and molecular mechanism and global genes that were mediated by lncRNA AFAP1-AS1 in non–small cell lung cancer (NSCLC) remain largely unknown. METHODS: Expression...
Autores principales: | Yin, Dandan, Lu, Xiyi, Su, Jun, He, Xuezhi, De, Wei, Yang, Jinsong, Li, Wei, Han, Liang, Zhang, Erbao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968553/ https://www.ncbi.nlm.nih.gov/pubmed/29793547 http://dx.doi.org/10.1186/s12943-018-0836-7 |
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