Integrating rare genetic variants into pharmacogenetic drug response predictions

BACKGROUND: Variability in genes implicated in drug pharmacokinetics or drug response can modulate treatment efficacy or predispose to adverse drug reactions. Besides common genetic polymorphisms, recent sequencing projects revealed a plethora of rare genetic variants in genes encoding proteins invo...

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Detalles Bibliográficos
Autores principales: Ingelman-Sundberg, Magnus, Mkrtchian, Souren, Zhou, Yitian, Lauschke, Volker M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968569/
https://www.ncbi.nlm.nih.gov/pubmed/29793534
http://dx.doi.org/10.1186/s40246-018-0157-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968569/
https://www.ncbi.nlm.nih.gov/pubmed/29793534
http://dx.doi.org/10.1186/s40246-018-0157-3

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