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The impact of septic stimuli on the systemic inflammatory response and physiologic insult in a preclinical non-human primate model of polytraumatic injury

BACKGROUND: Established animal trauma models are limited in recapitulating the pathophysiology of human traumatic injury. Herein, we characterize the physiologic insult and inflammatory response in two clinically relevant non-human primate (NHP) trauma models. METHODS: Mauritian Cynomolgus Macaques...

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Detalles Bibliográficos
Autores principales: Vicente, Diego A., Bradley, Matthew J., Bograd, Benjamin, Leonhardt, Crystal, Elster, Eric A., Davis, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968671/
https://www.ncbi.nlm.nih.gov/pubmed/29849508
http://dx.doi.org/10.1186/s12950-018-0187-6