Cargando…
Location dependent coordination chemistry and MRI relaxivity, in de novo designed lanthanide coiled coils
Herein, we establish for the first time the design principles for lanthanide coordination within coiled coils, and the important consequences of binding site translation. By interrogating design requirements and by systematically translating binding site residues, one can influence coiled coil stabi...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968752/ https://www.ncbi.nlm.nih.gov/pubmed/29899946 http://dx.doi.org/10.1039/c5sc04101e |