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Antagonistic role of GSK3 isoforms in glioma survival

GSK3 (Glycogen Synthase Kinase-3) function in brain is contributed by two distinct gene GSK3 alpha and GSK3 beta. Present findings indicate that imbalance in between GSK3 alpha and beta isoform contributes oncogenesis. In gliomas, GSK3 isoform specific functions are different then as reported for me...

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Detalles Bibliográficos
Autores principales: Vashishtha, Vidhi, Jinghan, Nupur, K.Yadav, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968773/
https://www.ncbi.nlm.nih.gov/pubmed/29805711
http://dx.doi.org/10.7150/jca.21248