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Lactoferrin- and RGD-comodified, temozolomide and vincristine-coloaded nanostructured lipid carriers for gliomatosis cerebri combination therapy

PURPOSE: Glioblastoma multiforme (GBM) is the most common malignant brain tumor originating in the central nervous system in adults. Based on nanotechnology such as liposomes, polymeric nanoparticles, and lipid nanoparticles, recent research efforts have been aimed to target drugs to the brain. METH...

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Detalles Bibliográficos
Autores principales: Zhang, Jicai, Xiao, Xiang, Zhu, Jianming, Gao, Ziyun, Lai, Xianliang, Zhu, Xingen, Mao, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968780/
https://www.ncbi.nlm.nih.gov/pubmed/29861635
http://dx.doi.org/10.2147/IJN.S161163