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Dual-drug nanomedicine with hydrophilic F127-modified magnetic nanocarriers assembled in amphiphilic gelatin for enhanced penetration and drug delivery in deep tumor tissue
INTRODUCTION: Deep penetration of large-sized drug nanocarriers into tumors is important to improve the efficacy of tumor therapy. METHODS: In this study, we developed a size-changeable “Trojan Horse” nanocarrier (THNC) composed of paclitaxel (PTX)-loaded Greek soldiers (GSs; ~20 nm) assembled in an...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968781/ https://www.ncbi.nlm.nih.gov/pubmed/29861633 http://dx.doi.org/10.2147/IJN.S161314 |