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High-performance reoxygenation from PLGA-PEG/PFOB emulsions: a feedback relationship between ROS and HIF-1α

BACKGROUND: Hypoxemia is one of the most common pathological processes in various clinical diseases. METHODS: A novel emulsion of poly(lactide-co-glycolide)-poly(ethylene glycol)/perfluorooctyl bromide has been developed to improve arterial hypoxemia through pulmonary drug delivery. Hypoxia-reoxygen...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Wang, Ruochen, Li, Niannian, Shen, Xi, Huang, Gang, Zhu, Jun, He, Dannong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968788/
https://www.ncbi.nlm.nih.gov/pubmed/29861634
http://dx.doi.org/10.2147/IJN.S155509