Design and preparation of derivatives of oleanolic and glycyrrhetinic acids with cytotoxic properties

BACKGROUND: The structural modification of natural products with the aim to improve the anticancer activity is a popular current research direction. The pentacyclic triterpenoid compounds oleanolic acid (OA) and glycyrrhetinic acid (GA) are distributed widely in nature. METHODS: In this study, vario...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Li, Yang, Huai, Xu-Dong, Zheng, Qing-Xuan, Wang, Wei, Li, Hui-Jing, Huai, Qi-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968802/
https://www.ncbi.nlm.nih.gov/pubmed/29861624
http://dx.doi.org/10.2147/DDDT.S166051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968802/
https://www.ncbi.nlm.nih.gov/pubmed/29861624
http://dx.doi.org/10.2147/DDDT.S166051

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