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Design and preparation of derivatives of oleanolic and glycyrrhetinic acids with cytotoxic properties

BACKGROUND: The structural modification of natural products with the aim to improve the anticancer activity is a popular current research direction. The pentacyclic triterpenoid compounds oleanolic acid (OA) and glycyrrhetinic acid (GA) are distributed widely in nature. METHODS: In this study, vario...

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Detalles Bibliográficos
Autores principales:	Wang, Rui, Li, Yang, Huai, Xu-Dong, Zheng, Qing-Xuan, Wang, Wei, Li, Hui-Jing, Huai, Qi-Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968802/ https://www.ncbi.nlm.nih.gov/pubmed/29861624 http://dx.doi.org/10.2147/DDDT.S166051

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