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Locally acting ACE‐083 increases muscle volume in healthy volunteers

Introduction: ACE‐083 is a locally acting follistatin‐based therapeutic that binds myostatin and other muscle regulators and has been shown to increase muscle mass and force in neuromuscular disease mouse models. This first‐in‐human study examined these effects. Methods: In this phase 1, randomized,...

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Detalles Bibliográficos
Autores principales: Glasser, Chad E., Gartner, Michael R., Wilson, Dawn, Miller, Barry, Sherman, Matthew L., Attie, Kenneth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969095/
https://www.ncbi.nlm.nih.gov/pubmed/29486514
http://dx.doi.org/10.1002/mus.26113