Ring‐Expanded N‐Heterocyclic Carbenes for Copper‐Mediated Azide–Alkyne Click Cycloaddition Reactions

A series of well‐defined copper(I) complexes bearing ring‐expanded N‐heterocyclic carbene (NHC) ligands has been applied to the azide–alkyne cycloaddition reaction. The obtained results notably showed that the six‐membered NHC ligands outperform well‐established five‐membered ones. [CuI(Mes‐6)] disp...

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Detalles Bibliográficos
Autores principales: Sebest, Filip, Dunsford, Jay J., Adams, Matthew, Pivot, Jeremy, Newman, Paul D., Díez‐González, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969269/
https://www.ncbi.nlm.nih.gov/pubmed/29861792
http://dx.doi.org/10.1002/cctc.201701992
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author Sebest, Filip
Dunsford, Jay J.
Adams, Matthew
Pivot, Jeremy
Newman, Paul D.
Díez‐González, Silvia
author_facet Sebest, Filip
Dunsford, Jay J.
Adams, Matthew
Pivot, Jeremy
Newman, Paul D.
Díez‐González, Silvia
author_sort Sebest, Filip
collection PubMed
description A series of well‐defined copper(I) complexes bearing ring‐expanded N‐heterocyclic carbene (NHC) ligands has been applied to the azide–alkyne cycloaddition reaction. The obtained results notably showed that the six‐membered NHC ligands outperform well‐established five‐membered ones. [CuI(Mes‐6)] displayed a remarkable catalytic activity while respecting the strict criteria for click reactions.
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spelling pubmed-59692692018-05-30 Ring‐Expanded N‐Heterocyclic Carbenes for Copper‐Mediated Azide–Alkyne Click Cycloaddition Reactions Sebest, Filip Dunsford, Jay J. Adams, Matthew Pivot, Jeremy Newman, Paul D. Díez‐González, Silvia ChemCatChem Full Papers A series of well‐defined copper(I) complexes bearing ring‐expanded N‐heterocyclic carbene (NHC) ligands has been applied to the azide–alkyne cycloaddition reaction. The obtained results notably showed that the six‐membered NHC ligands outperform well‐established five‐membered ones. [CuI(Mes‐6)] displayed a remarkable catalytic activity while respecting the strict criteria for click reactions. John Wiley and Sons Inc. 2018-03-07 2018-05-09 /pmc/articles/PMC5969269/ /pubmed/29861792 http://dx.doi.org/10.1002/cctc.201701992 Text en © 2017 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Full Papers
Sebest, Filip
Dunsford, Jay J.
Adams, Matthew
Pivot, Jeremy
Newman, Paul D.
Díez‐González, Silvia
Ring‐Expanded N‐Heterocyclic Carbenes for Copper‐Mediated Azide–Alkyne Click Cycloaddition Reactions
title Ring‐Expanded N‐Heterocyclic Carbenes for Copper‐Mediated Azide–Alkyne Click Cycloaddition Reactions
title_full Ring‐Expanded N‐Heterocyclic Carbenes for Copper‐Mediated Azide–Alkyne Click Cycloaddition Reactions
title_fullStr Ring‐Expanded N‐Heterocyclic Carbenes for Copper‐Mediated Azide–Alkyne Click Cycloaddition Reactions
title_full_unstemmed Ring‐Expanded N‐Heterocyclic Carbenes for Copper‐Mediated Azide–Alkyne Click Cycloaddition Reactions
title_short Ring‐Expanded N‐Heterocyclic Carbenes for Copper‐Mediated Azide–Alkyne Click Cycloaddition Reactions
title_sort ring‐expanded n‐heterocyclic carbenes for copper‐mediated azide–alkyne click cycloaddition reactions
topic Full Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969269/
https://www.ncbi.nlm.nih.gov/pubmed/29861792
http://dx.doi.org/10.1002/cctc.201701992
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