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Modelling the dopamine and noradrenergic cell loss that occurs in Parkinson's disease and the impact on hippocampal neurogenesis

Key pathological features of Parkinson's Disease (PD) include the progressive degeneration of midbrain dopaminergic (DA) neurons and hindbrain noradrenergic (NA) neurons. The loss of DA neurons has been extensively studied and is the main cause of motor dysfunction. Importantly, however, there...

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Detalles Bibliográficos
Autores principales: Ermine, Charlotte M., Wright, Jordan L., Frausin, Stefano, Kauhausen, Jessica A., Parish, Clare L., Stanic, Davor, Thompson, Lachlan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969306/
https://www.ncbi.nlm.nih.gov/pubmed/29431270
http://dx.doi.org/10.1002/hipo.22835