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Vonoprazan prevents ulcer recurrence during long-term NSAID therapy: randomised, lansoprazole-controlled non-inferiority and single-blind extension study

OBJECTIVE: To assess the non-inferiority of vonoprazan to lansoprazole for secondary prevention of non-steroidal anti-inflammatory drug (NSAID)-induced peptic ulcer (PU) and the safety of vonoprazan during extended use. DESIGN: A phase 3, 24-week, multicenter, randomised, double-blind (DB), active-c...

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Detalles Bibliográficos
Autores principales: Mizokami, Yuji, Oda, Kazunori, Funao, Nobuo, Nishimura, Akira, Soen, Satoshi, Kawai, Takashi, Ashida, Kiyoshi, Sugano, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969369/
https://www.ncbi.nlm.nih.gov/pubmed/28988197
http://dx.doi.org/10.1136/gutjnl-2017-314010