Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility

A key player in the intracellular trafficking network is cytoplasmic dynein, a protein complex that transports molecular cargo along microtubules. Vertebrate dynein’s movement becomes strikingly enhanced upon interacting with dynactin and a cargo-adapter, such as BicaudalD2. However, the mechanisms...

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Detalles Bibliográficos
Autores principales: Grotjahn, Danielle A., Chowdhury, Saikat, Xu, Yiru, McKenney, Richard J., Schroer, Trina A., Lander, Gabriel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969528/
https://www.ncbi.nlm.nih.gov/pubmed/29416113
http://dx.doi.org/10.1038/s41594-018-0027-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969528/
https://www.ncbi.nlm.nih.gov/pubmed/29416113
http://dx.doi.org/10.1038/s41594-018-0027-7

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