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Revisiting the Crabtree/Warburg effect in a dynamic perspective: a fitness advantage against sugar-induced cell death

The mechanisms behind the Warburg effect in mammalian cells, as well as for the similar Crabtree effect in the yeast Saccharomyces cerevisiae, are still a matter of debate: why do cells shift from the energy-efficient respiration to the energy-inefficient fermentation at high sugar concentration? Th...

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Detalles Bibliográficos
Autores principales: de Alteriis, Elisabetta, Cartenì, Fabrizio, Parascandola, Palma, Serpa, Jacinta, Mazzoleni, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969562/
https://www.ncbi.nlm.nih.gov/pubmed/29509056
http://dx.doi.org/10.1080/15384101.2018.1442622