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Modulation of formin processivity by profilin and mechanical tension

Formins are major regulators of actin networks. They enhance actin filament dynamics by remaining processively bound to filament barbed ends. How biochemical and mechanical factors affect formin processivity are open questions. Monitoring individual actin filaments in a microfluidic flow, we report...

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Detalles Bibliográficos
Autores principales: Cao, Luyan, Kerleau, Mikael, Suzuki, Emiko L., Wioland, Hugo, Jouet, Sandy, Guichard, Berengere, Lenz, Martin, Romet-Lemonne, Guillaume, Jegou, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969902/
https://www.ncbi.nlm.nih.gov/pubmed/29799413
http://dx.doi.org/10.7554/eLife.34176