In vivo evaluation of two tissue transglutaminase PET tracers in an orthotopic tumour xenograft model

BACKGROUND: The protein cross-linking enzyme tissue transglutaminase (TG2; EC 2.3.2.13) is associated with the pathogenesis of various diseases, including cancer. Recently, the synthesis and initial evaluation of two high-potential radiolabelled irreversible TG2 inhibitors were reported by us. In th...

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Detalles Bibliográficos
Autores principales: van der Wildt, Berend, Wilhelmus, Micha M. M., Beaino, Wissam, Kooijman, Esther J. M., Schuit, Robert C., Bol, John G. J. M., Breve, John J. P., Pasternack, Ralf, Lammertsma, Adriaan A., Windhorst, Albert D., Drukarch, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970127/
https://www.ncbi.nlm.nih.gov/pubmed/29802556
http://dx.doi.org/10.1186/s13550-018-0388-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970127/
https://www.ncbi.nlm.nih.gov/pubmed/29802556
http://dx.doi.org/10.1186/s13550-018-0388-2

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