High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer

Targeting exosome biogenesis and release may have potential clinical implications for cancer therapy. Herein, we have optimized a quantitative high throughput screen (qHTS) assay to identify compounds that modulate exosome biogenesis and/or release by aggressive prostate cancer (PCa) CD63-GFP-expres...

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Detalles Bibliográficos
Autores principales: Datta, Amrita, Kim, Hogyoung, McGee, Lauren, Johnson, Adedoyin E., Talwar, Sudha, Marugan, Juan, Southall, Noel, Hu, Xin, Lal, Madhu, Mondal, Debasis, Ferrer, Marc, Abdel-Mageed, Asim B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970137/
https://www.ncbi.nlm.nih.gov/pubmed/29802284
http://dx.doi.org/10.1038/s41598-018-26411-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970137/
https://www.ncbi.nlm.nih.gov/pubmed/29802284
http://dx.doi.org/10.1038/s41598-018-26411-7

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