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RNA synthesis is modulated by G-quadruplex formation in Hepatitis C virus negative RNA strand

DNA and RNA guanine-rich oligonucleotides can form non-canonical structures called G-quadruplexes or “G4” that are based on the stacking of G-quartets. The role of DNA and RNA G4 is documented in eukaryotic cells and in pathogens such as viruses. Yet, G4 have been identified only in a few RNA viruse...

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Detalles Bibliográficos
Autores principales: Jaubert, Chloé, Bedrat, Amina, Bartolucci, Laura, Di Primo, Carmelo, Ventura, Michel, Mergny, Jean-Louis, Amrane, Samir, Andreola, Marie-Line
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970142/
https://www.ncbi.nlm.nih.gov/pubmed/29802381
http://dx.doi.org/10.1038/s41598-018-26582-3