Blood lipid-related low-frequency variants in LDLR and PCSK9 are associated with onset age and risk of myocardial infarction in Japanese

Recent studies have revealed the importance of rare variants in myocardial infarction (MI) susceptibility in European populations. Because genetic architectures vary in different populations, we investigated how they contribute to MI susceptibility in Japanese subjects. We performed targeted sequenc...

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Detalles Bibliográficos
Autores principales: Tajima, Tomoyuki, Morita, Hiroyuki, Ito, Kaoru, Yamazaki, Tsutomu, Kubo, Michiaki, Komuro, Issei, Momozawa, Yukihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970143/
https://www.ncbi.nlm.nih.gov/pubmed/29802317
http://dx.doi.org/10.1038/s41598-018-26453-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970143/
https://www.ncbi.nlm.nih.gov/pubmed/29802317
http://dx.doi.org/10.1038/s41598-018-26453-x

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