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Mutations in BRCA1, BRCA2, and PALB2, and a panel of 50 cancer-associated genes in pancreatic ductal adenocarcinoma

Mutations in genes of the breast cancer susceptibility gene (BRCA) pathway, namely, BRCA1, BRCA2, and PALB2, can provide useful information for the efficacy of platinum-based or poly ADP-ribose polymerase inhibitors chemotherapeutic regimens. Pancreatic ductal adenocarcinoma (PDAC) is an important t...

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Detalles Bibliográficos
Autores principales: Takeuchi, Shoko, Doi, Manami, Ikari, Naoki, Yamamoto, Masakazu, Furukawa, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970161/
https://www.ncbi.nlm.nih.gov/pubmed/29802286
http://dx.doi.org/10.1038/s41598-018-26526-x