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Effect of multiple cyclic RGD peptides on tumor accumulation and intratumoral distribution of IRDye 700DX-conjugated polymers

Strategic delivery of IRDye 700DX (photosensitizer) is a key for improving its effect in photodynamic therapy. In this study, we have synthesized IRDye 700DX-conjugated polymers containing multiple cyclic RGD peptides to deliver IRDye 700DX selectively to tumor cells and tumor-associated blood vesse...

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Detalles Bibliográficos
Autores principales: Dou, Xuebo, Nomoto, Takahiro, Takemoto, Hiroyasu, Matsui, Makoto, Tomoda, Keishiro, Nishiyama, Nobuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970177/
https://www.ncbi.nlm.nih.gov/pubmed/29802410
http://dx.doi.org/10.1038/s41598-018-26593-0